Polyphenolic extracts from Italian Annurca apples may increase the excretion of cholesterol by an impressive 35% in healthy people, according to a new study.
Data published in the journal PharmaNutrition indicated that a novel nutraceutical product (the researchers refer to it as AMD), formulated with Annurca apple polyphenolic extracts, was able to decrease the solubility and absorption of cholesterol in the intestine, and may offer a natural solution to cholesterol management and cardiovascular support.
“AMD could be expected to better vehicle dimeric procyanidins to the micelle targets, thanks to its polar microencapsulated formulation,” wrote the researchers, led by Gian Carlo Tenore from University of Naples Federico II.
“This product may be regarded as a powerful tool to decrease cholesterol solubility at the duodenal tract and, thus, its intestinal bioavailability. Therefore, the present work proposes AMD as an effective remedy to lower cholesterol absorption in healthy subjects.”
There are already established ingredients for cholesterol management for product formulators, with the list dominated by sterols and stanols. Numerous clinical trials in controlled settings have reported that daily consumption of 1.5 to 3 grams of phyto-sterols/-stanols from foods can reduce total cholesterol levels by eight to 17%, representing a significant reduction in the risk of cardiovascular disease.
The US FDA approved health claim states that 1.3 grams of plant sterols per day as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease. (For plant stanols, the daily dose increases to 3.4 grams)
The new study suggests that an Annurca apple extract microencapsulated in maltodextrins may potentially offer another option to formulators. The apple-based ingredient was produced by Turin-based MB-Med Company.